Hypoglossal-Nerve Stimulation for Obstructive Sleep Apnea

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Hypoglossal nerve stimulation improves obstructive sleep apnea: 12-month outcomes.

Reduced upper airway muscle activity during sleep is a key contributor to obstructive sleep apnea pathogenesis. Hypoglossal nerve stimulation activates upper airway dilator muscles, including the genioglossus, and has the potential to reduce obstructive sleep apnea severity. The objective of this study was to examine the safety, feasibility and efficacy of a novel hypoglossal nerve stimulation ...

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Hypoglossal nerve conduction findings in obstructive sleep apnea.

Denervation of oropharyngeal muscles in obstructive sleep apnea (OSA) has been suggested by needle electromyography (EMG) and muscle biopsy, but little is known about oropharyngeal nerve conduction abnormalities in OSA. We sought to compare hypoglossal nerve conduction studies in patients with and without OSA. Unilateral hypoglossal nerve conduction studies were performed on 20 subjects with OS...

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Hypoglossal nerve stimulation for obstructive sleep apnea: A review of the literature

Objective To review the indications and clinical evidence supporting hypoglossal nerve stimulation (HNS) therapy for the treatment of moderate-to-severe obstructive sleep apnea (OSA). Methods Peer reviewed literature on hypoglossal nerve stimulation therapy for obstructive sleep apnea from 2001 to 2016. Results The only currently FDA-approved HNS device for the treatment of moderate-to-seve...

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Therapeutic electrical stimulation of the hypoglossal nerve in obstructive sleep apnea.

BACKGROUND Hypoglossal nerve stimulation has been demonstrated to relieve upper airway obstruction acutely, but its effect on obstructive sleep apnea is not known. OBJECTIVE To determine the response in obstructive sleep apnea to electrical stimulation of the hypoglossal nerve. METHODS Eight patients with obstructive sleep apnea were implanted with a device that stimulated the hypoglossal n...

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Hypoglossal nerve stimulation for treatment of obstructive sleep apnea (OSA): a primer for oral and maxillofacial surgeons

The prevalence of obstructive sleep apnea (OSA) is estimated to be 1-5% of the adult population world-wide, and in Korea, it is reported at 4.5% of men and 3.2% of women (Age 40 to 69 years old). Active treatment of OSA is associated with decrease in insulin resistance, cardiovascular disease, psychosocial problems, and mortality. Surgical treatment of OSA has evolved in the era of neuromodulat...

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ژورنال

عنوان ژورنال: New England Journal of Medicine

سال: 2014

ISSN: 0028-4793,1533-4406

DOI: 10.1056/nejme1314084